Immunosuppressive therapy in polymyositis

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Immunosuppressive therapy in polymyositis.

Immunosuppressive drugs were given to seven patients with polymyositis. The in-vitro activity of peripheral blood lymphocytes had previously been studied in five of these patients with findings suggestive of disturbed immunological processes. Some improvement occurred in five cases, but only in two was the improvement marked and sustained. In this small series of cases, the response to treatmen...

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Methotrexate therapy in polymyositis.

Polymyositis, an inflammatory disorder of skeletal and occasionally cardiac muscle, may present as a myopathy alone, as one manifestation of a multisystem disorder, especially systemic sclerosis (Medsger, Rodnan, Moossy, and Vester, 1968; Thompson, Bluestone, Bywaters, Dorling, and Johnson, 1969; Brock, 1934), systemic lupus erythematosus (White, 1959; Dubois, 1966), and Sjogren's syndrome (Bun...

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Immunosuppressive therapy in myocarditis.

Although there is general agreement on the favorable effect of immunosuppression in eosinophilic, granulomatous, giant-cell myocarditis and in lymphocytic myocarditis associated with connective tissue disorders and with rejection of a transplanted heart, its therapeutic role in lymphocytic inflammatory cardiomyopathy (ICM) is still debated. Previous retrospective studies reported a relevant cli...

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333 In a humble assessment of his own professional achievements, professor Tadeusz Orłowski paid great attention to the studies that aimed to elu‐ cidate the role of immunosuppressive therapies in glomerulopathies. In fact, to those who were his close co‐workers in the First Department of Medicine and then Transplantation Institute and to those who participated in the studies, it was essential ...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1971

ISSN: 0022-3050

DOI: 10.1136/jnnp.34.4.447